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Acetylsalicylic Acid

O-Acetylsalicylic Acid

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Packaging Details: 25 kilos/drum
Delivery Detail: 7 days after order

Acetylsalicylic Acid, also known by trade name Aspirin, is an acetyl derivative of salicylic acid that is a white, crystalline, weakly acidic substance, with melting point 137°C. It is useful in the relief of headache and muscle and joint aches.

MP 134-136 °C(lit.)
Density 1.35
FP 250 °C
storage temp.
Store at RT
Solubility H2O: 10 mg/mL at 37 °C
Water Solubility 3.3 g/L (20 ºC)
Stability Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, various other compounds such as iodides, iron salts, quinine salts, etc.
Chemical property This product is a white crystalline, with melting point 138 ~ 140 ℃, insoluble in water, soluble in alcohol, ether, etc.
Toxicity grading High toxic
Acute toxicity Oral-rat LD50: 200 mg/kg; Oral-mice LD50: 250 mg/kg
Flammable hazardous characteristics Flammable in fire; irritant gas would be decomposed out when heated.
Handling and storage characteristics Warehouse needs to be ventiIative and dry with low temperature; separate it from oxidant and food additives.
Fire extinguishing agent Water fog, foam, carbon dioxide, sandy soil.
Occupational standard TWA 5 mg/m3
General Description Odorless white crystals or crystalline powder with a slightly bitter taste.
Air & Water Reactions Slowly hydrolyzes in moist air. Has been involved in dust cloud explosions. Water insoluble. Solution in water is acid to methyl red indicator.
Reactivity Profile The active ingredient in common aspirin. Incompatible with oxidizers and strong acids. Also incompatible with strong bases. May react with water or nucleophiles (e.g. amines and hydroxy groups). May also react with acetanilide, amidopyrine, phenazone, hexamine, iron salts, phenobarbitone sodium, quinine salts, potassium and sodium iodides, alkali hydroxides, carbonates, stearates and paracetanol.
Fire Hazard Acetylsalicylic acid is combustible.
Applications 1.Acetylsalicylic acid is the raw material for rodenticide intermediates 4-hydroxycoumarin.
2.Used to make outdoor structural members and equipment parts exposed in highlights, such as the automobile body, agricultural machinery parts, meters and electric lamps, road marking, etc.
3.It is the earliest applied, the most popular and the most common antipyretic analgesics anti-rheumatism medicine, has aspects of pharmacological effects as antipyretic-analgesic and anti-inflammatory, anti-platelet aggregation and works quickly and effectively. Overdosage can be easily diagnosed and treated, with rare allergic reactions. Often used to cold fever, headache, neuralgia, joint ache, muscle pain, rheumatic fever, acute wet sex arthritis, rheumatoid arthritis and toothache, etc. Listed in National Essential Medicine List. Acetylsalicylic acid also works as an intermediate of other medicines.
Usage Analgesic; antipyretic; anti-inflammatory; antithrombotic
Item Standard
Clarity and Color of Solution clear and colorless
Heavy metals 20ppm max
Salicylic acid 0.05% max
Related substances 0.25% max
Loss on drying 0.5% max
Sulphated ash 0.1% max
Assay 99.5%~101%

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