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Analgin

Metamizole sodium

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Package and Storage:

Packaging Details: 25 kilos/drum
Delivery Detail: 7 days after order

Specifications:
Analgin, Metamizole sodium is used for the treatment of pains of different origin and variable intensity.

storage temp. 2-8°C
Stability
Stable. Incompatible with strong oxidizing agents.
Usage A non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Blocks PGE2-induced hyperalgesia in several models.
TEST SPECIFICATION RESULT
APPEARANCE WHITE, FREE FLOWING, GRANULES CONFORMS
IDENTIFICATION CONFORMS CONFORMS
ASSAY(ON DRY BASIS) 87.5~92.5% 89.5%
RELATED SUBSTANCE P-CHLOROACETANILIDE
OTHER IMPURITIES
≤0.001%
≤0.20%
<0.001%
<0.20%
LOSS ON DRYING 0.5~2.5% 1.5%
BULK DENSITY 0.5~0.70G/CM3 0.61G/CM3
DISINTEGRATION ≤5MIN 2’0’’
DISSOLUTION ≥80% 98.2%
HEAVY METALS ≤0.001% < 0.001%
HARDNESS ≥7KGF 9.1KGF
SIEVE TEST
RETAINED ON USS20 ≤15% 12.0%
RETAINED ON USS40 ≥40% 345%
RETAINED ON USS60 ≥50% 66%
RETAINED ON USS80 ≥65% 76%
RETAINED ON USS100 ≤80% 78%
MICROBIOLOGICAL TEST
TOTAL VIABLE MICROBIAL COUNT <10/G <10
MOLD <50/G <50/G
COLON BACILLUS NONE NONE

 
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