HOME > Dihydroergotoxine mesylate
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Hydergine was identified from a review of substances being promoted as nootropics or “smart drugs” for cognition enhancement in well persons of all ages. Hydergine is also a prescription drug for the treatment of senility and cerebrovascular insufficiency.
Hydergine is an ergot alkaloid. Ergot alkaloids have a wide field of therapeutic application, and their biological activities are strongly dependent on their structural conformation. Despite their widespread use, little information on the carcinogenic or mutagenic potential of hydergine or closely related ergot alkaloids was found in the available literature. Information on the genotoxicity of hydergine was mixed and not completely consistent with the results reported for the closely related compound, ergotamine.
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