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Dinoprostone

prostaglandin-e2

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PRODUCT NAME: Dinoprostone
CAS NUMBER: 363-24-6

MP 66-68 °C
alpha -85.5 º (c=1, C2H5OH)
storage temp.
-20°C
Solubility ethanol: 1 mg/mL
Water Solubility insoluble
Biological Activity Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Binds with high affinity to EP 1 , EP 2 , EP 3 and EP 4 receptors (K d values range between ~ 1-10 nM). Influences a wide range of processes including inflammation, smooth muscle relaxation, fertility and gastric mucosal integrity. Regulates vertebrate hematopoietic stem cell (HSC) homeostasis.
Usage The most common and most biologically potent of mammalian prostaglandins. Isolated from sheep prostate. Oxytocic; abortifacient.

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