HOME > Doxycycline HCl
Doxycycline HCl
Packaging Details: | 25KG/DRUM |
---|---|
Delivery Detail: | prompt shipment |
storage temp. |
0-6°C |
Usage | Doxycycline hydrochloride is a salt prepared from doxycycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. |
Items | Specifications | Results |
Appearance | Yellow crystalline powder | Complies |
PH Value | 2.0 ~ 3.0 | 2.4 |
Specific optical rotation | -105°~-120° | -110° |
Specific absorbance | At 349nm: 300 ~ 335 | 317 |
Light absorbing impurities | At 490nm ≤0.07 | 0.03 |
Related substances |
6-Epidoxycycline ≤2.0% Methacycline ≤2.0% Disregard limit ≤0.1% Any individual impurity ≤0.5% |
Complies Complies Complies Complies |
Ethanol | 4.3% ~ 6.0%(m/m) | 4.8% |
Heavy metals | ≤50ppm | Complies |
Water | 1.4% ~ 2.8% | 2.0% |
Sulphated ash | ≤0.4% | 0.08% |
Assay |
95.0% ~ 102.0% of C22H25CIN2O8 (anhydrous,ethanol-free substance) |
98.3% |
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