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Doxycycline HCl

Doxycycline HCl

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Packaging Details: 25KG/DRUM
Delivery Detail: prompt shipment

Specifications:
PRODUCT NAME: Doxycycline hydrochloride
CAS NUMBER: 10592-13-9

storage temp.
0-6°C
Usage Doxycycline hydrochloride is a salt prepared from doxycycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.
Items Specifications Results
Appearance Yellow crystalline powder Complies
PH Value 2.0 ~ 3.0 2.4
Specific optical rotation -105°~-120° -110°
Specific absorbance At 349nm: 300 ~ 335 317
Light absorbing impurities At 490nm ≤0.07 0.03
Related substances 6-Epidoxycycline ≤2.0%  
Methacycline ≤2.0%  
Disregard limit ≤0.1%
Any individual impurity ≤0.5%
Complies
Complies
Complies
Complies
Ethanol 4.3% ~ 6.0%(m/m) 4.8%
Heavy metals ≤50ppm Complies
Water 1.4% ~ 2.8% 2.0%
Sulphated ash ≤0.4% 0.08%
Assay 95.0% ~ 102.0% of C22H25CIN2O8
(anhydrous,ethanol-free substance)
98.3%

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