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Lansoprazole

Lansoprazole

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Packaging Details: 25 kilos/drum
Delivery Detail: 7 days after order

Specifications:
Lansoprazole is a proton-pump inhibitor in the same pharmacologic class as omeprazole. Lansoprazole has been marketed for many years and is one of several PPIs available.Lansoprazole is a racemate [1:1-mixture of the enantiomers dexlansoprazole (Kapidex andlevolansoprazole].

MP 178-182°C dec.
storage temp.
2-8°C
Biological Activity H + ,K + -ATPase inhibitor (IC 50 = 6.3 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.09 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro . Also blocks swelling-dependent chloride channel (ICIswell) in NIH3T3 fibroblasts. More potent than omeprazole (5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole ).
Usage Used as a gastric proton pump inhibitor. An antiulcerative. Treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, duodenal ulcers, Helicobacter pylori (H. pylori) infections,stomach ulcers, prevention of stomach ulcers in those people taking non-steroidal anti-inflammatory drugs (NSAIDs)

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