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Meropenem

Meropenem

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Product name: Meropenem / CAS: 96036-03-2
Meropenem is bactericidal except against Listeria monocytogenes where it is bacteriostatic. It inhibits bacterial wall synthesis like other beta-lactam antibiotics. In contrast to other beta-lactams, it is highly resistant to degradation by beta-lactamases or cephalosporinases. Resistance generally arises due to mutations in penicillin binding proteins, production of metallo-beta-lactamases, or resistance to diffusion across the bacterial outer membrane. Unlike imipenem, it is stable to dehydropeptidase-1 and can therefore be given without cilastatin

Items Specifications
Appearance
White or yellowish crystalline powder
Identification Positive
pH 7.3 ~ 8.3
Loss on Drying 9.0 ~ 12.0%
Limit of Acetone ≤0.05%
Content of Sodium 7.3 ~ 10.9%
Bacterial Endotoxins ≤0.125Eu/mg
Related Substance Meets the requirements
Sterility Meets the requirements
Assay (on dried basis) Meropenem ≥78.0%
Usage antineoplastic, PDGF receptor blocker, immunomodulator

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