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Mesalazine

5-Aminosalicylic acid

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Supply 5-Aminosalicylic acid /Mesalazine

MP 275-280 °C (dec.)(lit.)
Flash Point 198.1°C
Boiling Point(°C) 403.9°C at 760 mmHg
storage temp.
2-8°C
Water Solubility <0.1 g/100 mL at 21 ºC
Decomposition 279-281 ºC
Stability Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
General Description Odorless white to pinkish crystals or purplish-tan powder. Aqueous solutions acidic (pH approximately 4.1 at 0.8 mg/L water).
Air & Water Reactions Sensitive to moisture. Water insoluble.
Reactivity Profile 5-Aminosalicylic acid is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizers.
Fire Hazard Flash point data for 5-Aminosalicylic acid are not available; however, 5-Aminosalicylic acid is probably combustible.
Appearance 1.  White or light red crystal
2.  It can dissolve in many organic solvents
Medical Application 5 – aminosalicylic acid(5-ASA drugs name mesalazine, Masalazine) is an important chemical raw material medicine and dye.
1.Drug treatment of chronic colitis is a methyl pyridine Liu main raw material for ammonia, which itself has a similar therapeutic effect.
2.5 – aminosalicylic acidas hydroxyl and carboxyl on the ring with three lively reactive groups, can be a variety of reactions, so the dye industry.
Usage The active metabolite of Sulfasalazine (S699084). Anti-inflammatory (gastrointestinal). For the treatment of active ulcerative proctitis.

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