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Naproxen Sodium

Naproxen Sodium

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Packaging Details: 25kg/drum
Delivery Detail: prompt shipment

Specifications:
PRODUCT NAME: Naproxen Sodium
CAS NUMBER: 26159-34-2

MP 250-251°C
storage temp.
Desiccate at RT
Standard GMP&FDA approval
Biological Activity Non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
Usage An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory. Naproxen (Aleve, Anaprox) is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively
Item Standard(USP31)
Appearance White to almost white crystalline powder
Infrared absorption The infrared absorption spectrum is concordant with the reference spectrum
Ultraviolet absorption Absorptivities at 272nm, calculated on the dried base, do not differ by more than 3%
Specific rotation -17.0°~ -15.3°
Loss on drying ≤1.0%
Heavy metals ≤0.002%
Free Naproxen ≤1.0%
Impurity D( in house) ≤0.10%
Impurity E( in house, Impurity C in EP) ≤0.10%
Any other impurity ≤0.10%
Total impurities ≤1.0%
Toluene ≤50ppm
Methanol ≤50ppm
Hthanol ≤100ppm
Assay( On the dried basis ) 98.0%~102.0%

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