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Nimesulide

Nimesulide

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Package and Storage:

Packaging Details: 25KG/paper barrel or packed according to the requirements of customers
Delivery Detail: 15 days after order

Specifications:
Product name: Nimesulide / CAS: 51803-78-2
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. It has a multifactorial mode of action and is characterized by a fast onset of action.

Items Specifications
MP
140-146°C
storage temp. 2-8°C
Stability Stable. Incompatible with strong oxidizing agents.
Biological Activity
Selective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo . Reported to produce fewer gastrointestinal side effects than standard NSAIDs.
Usage
Labelled Nimesulide (N477500). Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-α production.

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