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Ranitidine HCl

Ranitidine hydrochloride

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Package and Storage:

Packaging Details: 25KG/drum
Delivery Detail: prompt shipment

Specifications:
Product name: Ranitidine hydrochloride / CAS: 66357-35-5
1. H2-antagonist
2. Commonly used in treatment of disease (PUD) and disease (GERD).

Items Specifications
MP
69-70°C
storage temp. Desiccate at +4°C
solubility H2O: 1.8 mg/mL
Water Solubility
24.7 mg/mL
Identification
Positive reaction
PH
4.5-6.0
Loss on drying
Not more than 0.75%
Residue on ignition
Not more than 0.1%
Chromatographic purity
Ranitidine Related Compound B not more than 0.5%
Any other impurity not more than 0.3%
The sum of all impurities not more than 1.0%
Organic volatile impurities
Meets the requirements
Residual solvents
Meets the requirements
Assay(dry substance)
97.5%-102.0%
Biological Activity
Potent, selective and competitive histamine H 2 receptor antagonist (pA 2 = 6.95-7.2). In vivo, inhibits gastric acid secretion induced by histamine, pentagastrin, bethanecol and food. Also inhibits aspirin-induced gastric lesions.

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