HOME > Ranolazine dihydrochloride
|Delivery Detail:||prompt shipment|
||Desiccate at RT|
|Solubility||H2O: 10 mg/mL, soluble|
|Appearance||white or off- white powder|
|Biological Activity||Antianginal agent with antiarrhythmic properties that acts as a partial fatty acid oxidation inhibitor. Activates pyruvate dehydrogenase in ischemic myocytes to promote glucose oxidation, switching substrate utilization from fatty acids to glucose. Also shown to inhibit late I Na and I Kr currents.|
|Usage||Anti-ischemic agent which modulates myocardial metabolism. Antianginal. treatment of angina and congestive heart failure|
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