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Ranolazine dihydrochloride

Ranolazine DiHCI

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Packaging Details: 25kg/drums
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Specifications:
PRODUCT NAME: Ranolazine dihydrochloride
CAS NUMBER: 95635-56-6

MP 222-229.5 °C(lit.)
storage temp.
Desiccate at RT
Solubility H2O: 10 mg/mL, soluble
Appearance white or off- white powder
Biological Activity Antianginal agent with antiarrhythmic properties that acts as a partial fatty acid oxidation inhibitor. Activates pyruvate dehydrogenase in ischemic myocytes to promote glucose oxidation, switching substrate utilization from fatty acids to glucose. Also shown to inhibit late I Na and I Kr currents.
Usage Anti-ischemic agent which modulates myocardial metabolism. Antianginal. treatment of angina and congestive heart failure

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