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Roxithromycin

Roxithromycin

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PRODUCT NAME: Roxithromycin
CAS NUMBER: 80214-83-1
Roxithromycin used for sensitive strain caused by infection, especially upper and lower respiratory tract infection, ent infection, genital (neisseria gonorrhoeae infection except) and skin infections. Roxithromycin main indications for sensitive bacteria of facial features, respiratory, reproductive system and skin infections.

MP 111-118°C
storage temp.
2-8°C
Usage Roxithromycin was one of the new generation erythromycins introduced in the 1980s. Improved acid stability was achieved by converting the 9-keto group to the more stable oxime and alkylation of the oxime to provide the methoxyethoxymethyl ether oxime. In vivo, roxithromycin exhibits higher tissue levels and a longer half-life while being slightly less potent than erythromycin in vitro.
ITEMS SPECIFICATIONS RESULTS
Appearance A white or almost white crystalline powder A white crystalline powder
Specific rotation -82°~-87° -85.8°
Identification (IR) (1)should be consistent for the trying solution prominent peak retention time with the comparison solution prominent peak retention time
(2)this infrared light absorption atlas should be consistent with the comparison atlas
Consistent

Consistent

related substance The single impurity peak area does not have to be bigger than the comparison solution prominent peak area 1.5 times
Each miscellaneous quality area of with can not be big in check against aqua a lord the area of 4.5times
0.9

4.2

Alkalinity pH 8.0~10.0 9.0
Water less  than 3.0% 2.8%
Residue on ignition less than 0.1% 0.06%
Heavy metals less than 10ppm less than 10ppm
on the anhydrous basis more than 94.0% 95.9%
Conclusion The material conform with  BP2002

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