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Sorafenib

Sorafenib tosylate

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Packaging Details: 1g/bag, 10g/bag, 100g/bag, 1kg /bag, 25kg/drum
Delivery Detail: within 18days after confirm the order

Specifications:
PRODUCT NAME: Sorafenib
CAS NUMBER: 284461-73-0

MP 202-204°C
storage temp.
-20°C Freezer
Usage Multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic. Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively.
Function Sorafenib is used for the treatment of cancers.
Package & Storage Sorafenib Powder is stored in a cool and dry well-closed container,the temperature should be lower than 25°C, the relative humidity should not exceed 50%.
Analysis Test Specification Result
Description White to off white crystalline powder Comply
Melting point 166-170°C 168.3-169.5°C
Identification Positive reaction Positive reaction
Related substances ≤1.0% 0.15%
Loss on drying ≤0.5% 0.08%
Residue on ignition ≤0.1% 0.01%
Chloride ≤0.014% <0.014
Heavy Metals ≤20ppm ≤20ppm
Clarity of solution Conform to standard Complies
Microbial Limit ≤20ppm ≤20ppm
Assay ≥99.0% 99.31%

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